What is Cushing’s Syndrome?

Cushing’s is a hormonal disorder caused by prolonged exposure to high levels of cortisol—the body’s primary stress hormone. Cortisol plays an essential role in regulating inflammation and controlling how the body uses carbohydrates, fats, and proteins. However, when cortisol levels become excessive, a wide range of symptoms can appear.

These symptoms may include acne, a “buffalo hump” (fat accumulation on the upper back and neck), elevated blood sugar, excessive thirst, fatigue, frequent urination, headaches, high blood pressure, increased hair growth, menstrual irregularities, central obesity (weight gain mainly in the midsection), a round, full face known as “moon face,” purple stretch marks, muscle weakness, and psychological symptoms such as mood swings, depression, anxiety, and panic attacks.

 Cushing’s Syndrome is a complex endocrine disorder often shrouded in uncertainty due to its subtle and varied symptoms. Misdiagnosis is a common hurdle, delaying effective treatment and impacting patient quality of life.

The Challenge of Misdiagnosis

Cushing’s affects women more often than men, and the onset of symptoms can be gradual, often making diagnosis difficult.

Symptoms such as weight gain, fatigue, hypertension, and mood changes often mimic other conditions. This overlap results in frequent diagnostic errors, underscoring the need for heightened clinical awareness.